About the Product
Life Pro Nutrition's DigeZyme is a digestive enzyme supplement in vegetable capsules, based on the patented multienzyme complex DigeZyme® (Sabinsa Corporation, USA/India), with 200 mg per capsule. DigeZyme® is a blend of 5 digestive enzymes of microbial origin obtained by controlled fermentation with specific fungi, each specialized in digesting a different macronutrient class: alpha-amylase (carbohydrates and starches), protease (proteins), lipase (fats), lactase (lactose), and cellulase (vegetable fibers). Unlike digestive enzymes of animal origin (such as bovine/porcine pancreatin, often used in conventional digestive enzyme supplements), all DigeZyme® enzymes are of microbial origin, making the product suitable for vegans. 1 capsule per day with one of the main meals. 120 capsules (4 months of supplementation). Vegan.
Benefits
DigeZyme®: Sabinsa's patented multienzyme complex with 5 full-spectrum digestive enzymes:
DigeZyme® is the patented digestive enzyme formulation developed by Sabinsa Corporation (the same company responsible for BioPerine®, the patented piperine found in Life Pro's Curcumin + Bioperine product), produced by fermentation of non-pathogenic fungi under GMP conditions. The differentiator of DigeZyme® compared to generic digestive enzymes is the specific combination of 5 enzymes with a complementary substrate spectrum, covering all major macronutrient classes and food components, with enzymatic activities (expressed in units per capsule) calibrated to be effective under the physiological conditions of the human gastrointestinal tract (acidic gastric pH and neutral to alkaline intestinal pH). DigeZyme® enzymes are specifically resistant to denaturation by gastric proteases and inactivation by gastric hydrochloric acid, which is a critical technical advantage for enzymes of microbial origin compared to animal enzymes (which are equally sensitive to acidic pH but have an optimal activity temperature closer to body temperature).
Alpha-amylase (4800 U/capsule, from Aspergillus oryzae): digestion of complex carbohydrates and starches:
Alpha-amylase is the enzyme responsible for hydrolyzing the alpha-1,4-glycosidic bonds of starch (amylose and amylopectin), glycogen, and other polysaccharides, converting them into oligosaccharides and maltose which are subsequently hydrolyzed by intestinal mucosal disaccharidases (maltase, sucrase, isomaltase) into absorbable glucose. Salivary and pancreatic alpha-amylase are the endogenous enzymes that normally perform this function; microbial alpha-amylase from DigeZyme® complements endogenous digestive capacity, being especially relevant in: people with exocrine pancreatic insufficiency (which affects pancreatic amylase production), people who consume large volumes of complex carbohydrates (such as strength and endurance athletes with starch-rich diets), and people who experience bloating, distension, and abdominal discomfort after meals rich in incompletely digested carbohydrates.
Protease (1200 U/capsule, from Aspergillus oryzae): optimization of protein digestion and amino acid bioavailability:
DigeZyme® protease is a blend of fungal-derived endopeptidases and exopeptidases that catalyzes the hydrolysis of peptide bonds in dietary proteins, progressively converting them into short-chain peptides and absorbable free amino acids. Protein digestion normally involves gastric pepsin (which initiates protein hydrolysis at the acidic pH of the stomach) followed by pancreatic proteases (trypsin, chymotrypsin, elastase) in the small intestine; DigeZyme® fungal protease has activity over multiple pH ranges (including acidic and neutral pH), complementing and accelerating protein digestion throughout the entire gastrointestinal tract. This property is especially relevant for athletes who consume large amounts of protein (especially slower-absorbing protein like casein, pea protein, and soy protein) and for people with hypochlorhydria (low production of gastric hydrochloric acid, a condition prevalent after age 50 and in chronic users of proton pump inhibitors).
Lipase (200 U/capsule, from Rhizopus oryzae): fat digestion and absorption of fat-soluble vitamins:
Lipase is the enzyme responsible for hydrolyzing triglycerides (the predominant dietary fats) into free fatty acids and monoglycerides, which are the products that enter lipid micelles for intestinal absorption. Endogenous pancreatic lipase is produced by the pancreas and secreted into the duodenum; DigeZyme® fungal lipase (from Rhizopus oryzae) has activity over a broader pH range than pancreatic lipase, being functional in both the stomach (pH 2 to 4) and the small intestine (pH 6 to 8). More effective fat digestion has a direct impact not only on the absorption of fatty acids themselves but also on the absorption of fat-soluble vitamins (A, D, E, and K) which depend on lipid micelles formed by fat digestion products to be absorbed. People who consume fat-soluble vitamin supplements (such as Vitamin D3, Vitamin E, or Omega-3) indirectly benefit from DigeZyme® lipase, which optimizes the formation of the lipid micelles necessary for the absorption of these compounds.
Lactase (800 U/capsule): the key enzyme for people with lactose intolerance or sensitivity:
Lactase (beta-galactosidase) is the enzyme that hydrolyzes lactose (milk disaccharide) into glucose and galactose, the absorbable monosaccharides. Endogenous lactase production by the small intestinal mucosa progressively decreases after weaning in most of the adult human population, especially in populations of African, Asian, and South American origin (adult hypolactasia, the most common genetically determined form of lactose intolerance). When undigested lactose reaches the colon, it is fermented by the intestinal microbiota with the production of gases (hydrogen, carbon dioxide, methane) and short-chain fatty acids, causing flatulence, borborygmi, distension, and osmotic diarrhea. DigeZyme® lactase pre-hydrolyzes lactose in the small intestine, eliminating or significantly reducing these symptoms in people with lactose sensitivity, and is especially relevant in the context of sports protein supplementation where whey protein concentrates (WPC) contain amounts of lactose that can be problematic.
Cellulase (40 U/capsule, from Trichoderma longibrachiatum): digestion of indigestible vegetable fibers:
Cellulase is an enzyme that hydrolyzes cellulose (the main component of plant cell walls) into glucose. The human body does not produce cellulase endogenously, so the cellulose in plant cell walls is normally not digested and passes intact into the colon, where it is fermented by the microbiota. DigeZyme® cellulase helps break down the cell walls of plant foods, releasing intracellular nutrients (including proteins, carbohydrates, vitamins, and minerals) that are encapsulated within plant cells. In diets rich in raw vegetables and plant-based foods, cellulase improves the bioavailability of plant nutrients and reduces excessive cellulose fermentation in the colon that can contribute to flatulence and digestive discomfort.
DigeZyme® as a functional excipient in sports proteins: the industry standard for premium protein supplements:
DigeZyme® is also one of the most widely used functional excipients in premium sports proteins, being the enzymatic complex present in Dirty Squads proteins (ISO 90X and ISO 80X) sold at Brothers Club. The inclusion of DigeZyme® in proteins serves precisely to optimize the digestion of concentrated/isolated whey proteins, which in doses of 25 to 30 g can overload the endogenous proteolytic digestive capacity of some people, especially when consumed rapidly post-workout. Life Pro's DigeZyme® supplement allows the user to supplement independently with the same enzymatic complex, without being limited to proteins that already include it in their formula.
Uses
Recommended dose: Take 1 capsule per day with one of the main meals. It should be taken immediately before or during the meal (not after) so that the enzymes are present in the gastrointestinal tract simultaneously with the food to be digested. For especially abundant meals or meals rich in difficult-to-digest foods (large amounts of animal proteins, dairy products, meals rich in fat or vegetable fiber), efficacy is maximized when the capsule is taken at the beginning of the meal.
