{"product_id":"product_69abafb5-2322-4956-bb00-480f4110dc07","title":"HSN - COLLAGEN JOINT HEALTH POWDER | 15g","description":"\u003ch2 class=\"text-text-100 mt-3 -mb-1 text-[1.125rem] font-bold\"\u003eAbout the Product\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eHSN's EssentialSeries Joint Health Collagen Powder is a complete joint health support formula, developed by HSN experts with low molecular weight hydrolysed bovine collagen peptides as the main ingredient, enriched with a wide spectrum of vitamins (C, D, E, K, B6, B12, Folic Acid), minerals (Calcium, Phosphorus, Magnesium, Copper), functional cartilage compounds (MSM, D-Glucosamine, Chondroitin) and natural anti-inflammatory plant extracts (Turmeric, Boswellia serrata and Black Pepper). The collagen used is of bovine origin, produced from the connective tissue of meat cuts intended for human consumption, from pasture-raised animals without hormones or antibiotics, with controlled hydrolysis ensuring low molecular weight peptides with high bioavailability. Suitable for people allergic to fish and shellfish (it is not of marine origin). GMO-free. Easy-to-dissolve powder format, available in Orange, Peach, Cherry and other flavours.\u003c\/p\u003e\n\u003ch2 class=\"text-text-100 mt-3 -mb-1 text-[1.125rem] font-bold\"\u003eBenefits\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eLow molecular weight hydrolysed bovine collagen peptides for maximum bioavailability:\u003c\/strong\u003e Hydrolysed collagen is produced by the enzymatic hydrolysis of native collagen, breaking the long tripeptide chains into low molecular weight peptides (typically 2000 to 5000 Daltons) that are absorbed intact in the small intestine and transported to the bloodstream without the need for further digestion. Kinetic studies document that isotope-labelled collagen peptides are detected in plasma, skin, cartilage and connective tissues within hours of ingestion, confirming their bioavailability and arrival at the target tissue. HSN's controlled hydrolysis of bovine collagen ensures a consistent low molecular weight that maximises absorption, unlike non-hydrolysed collagen (gelatine) which requires complete gastrointestinal digestion with variable absorption.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eTriple joint protection: MSM + D-Glucosamine + Chondroitin:\u003c\/strong\u003e The three functional compounds included in the formula act on different aspects of joint health in a complementary and synergistic way. MSM (Methylsulfonylmethane) is a source of bioavailable organic sulphur, essential for the synthesis of collagen and glycosaminoglycans, with documented anti-inflammatory properties in modulating pro-inflammatory cytokines (IL-1β, TNF-α) that are involved in the degradation of articular cartilage. D-Glucosamine is an aminomonosaccharide precursor of glycosaminoglycans and proteoglycans that constitute the extracellular matrix of articular cartilage, with clinical studies documenting a reduction in joint pain and an improvement in function in osteoarthritis. Chondroitin is a structural glycosaminoglycan of articular cartilage, with water retention properties in the cartilaginous matrix (providing elasticity and resistance to compression) and inhibition of cartilage-degrading enzymes (MMP-3, MMP-13).\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eBoswellia serrata for anti-inflammatory modulation of the joint:\u003c\/strong\u003e Boswellia serrata extract (Indian frankincense) is one of the herbal anti-inflammatories with the strongest scientific evidence base for joint health. Boswellic acids, especially AKBA (3-O-acetyl-11-keto-β-boswellic acid), specifically inhibit the enzyme 5-lipoxygenase (5-LOX), the metabolic pathway responsible for the production of inflammatory leukotrienes that contribute to synovial inflammation and articular cartilage degradation. Unlike conventional NSAIDs that inhibit both COX-1 and COX-2 (with potential gastrointestinal injury), Boswellia preferentially acts on the 5-LOX pathway, with a better gastrointestinal tolerance profile and without the risk of gastric mucosal injury associated with COX-1 inhibition.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eVitamin C for collagen synthesis: the most direct EFSA health claim for joints:\u003c\/strong\u003e Vitamin C (ascorbic acid) is an indispensable enzymatic cofactor for proline hydroxylase and lysyl hydroxylase enzymes, responsible for the hydroxylation of proline and lysine during collagen synthesis. Without sufficient Vitamin C, the synthesised collagen has a defective structure and lower mechanical resistance, compromising the integrity of all connective tissues. EFSA specifically recognises that Vitamin C contributes to normal collagen formation for the normal function of cartilage, one of the most relevant and directly applicable health claims to the context of this joint health formula.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eTurmeric (curcumin) and Black Pepper (piperine) for anti-inflammatory potentiation and bioavailability:\u003c\/strong\u003e Curcumin, the bioactive compound of Curcuma longa rhizome, has widely documented anti-inflammatory and antioxidant properties, acting on multiple inflammatory pathways including the inhibition of the nuclear factor NF-κB and the modulation of pro-inflammatory cytokines. The main limitation of conventional curcumin is its very low oral bioavailability. The inclusion of Black Pepper extract (piperine) in the formula partially solves this problem: piperine inhibits the intestinal and hepatic first-pass enzymes (CYP3A4, UGT) that metabolise curcumin, increasing its oral bioavailability up to 20 times, as documented in published clinical studies.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eVitamin D for bone health and muscle function:\u003c\/strong\u003e Vitamin D is an essential cofactor for intestinal calcium absorption and normal bone mineralisation, being especially relevant in contexts of joint and bone health where maintaining bone mineral density is critical for protecting joints from mechanical overload. EFSA recognises that Vitamin D contributes to the maintenance of normal bones and teeth and normal muscle function.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eMagnesium, Calcium, Phosphorus and Copper for bone health and connective tissue synthesis:\u003c\/strong\u003e The four included minerals cover essential functions for the integrity of the musculoskeletal system: Calcium and Phosphorus for bone matrix mineralisation; Magnesium for normal muscle function and as a cofactor for hundreds of enzymes including those involved in protein synthesis; and Copper as a cofactor for lysyl oxidase, the enzyme responsible for the cross-linking of mature collagen that provides mechanical strength to connective tissue.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eBovine collagen, free from marine allergens, from pasture-raised animals:\u003c\/strong\u003e HSN collagen comes from pasture-raised cows without hormones, antibiotics or conventional feed, processed from the connective tissue of meat cuts intended for human consumption. This origin is especially relevant for people with allergies or intolerances to fish and shellfish (which excludes a large part of the marine collagens available on the market), guaranteeing a high-quality bovine alternative without allergenic risk for this group.\u003c\/p\u003e\n\u003ch2 class=\"text-text-100 mt-3 -mb-1 text-[1.125rem] font-bold\"\u003eDirections\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eRecommended dose:\u003c\/strong\u003e Dissolve the dose indicated on the packaging (typically 1 scoop, ~15 to 20 g) in 200 to 300 ml of cold water or any preferred drink. Consume in the morning, preferably on an empty stomach or with a light meal, to maximise the absorption of collagen peptides. Continued use for at least 3 months is necessary for consistent results.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eTiming and consistency:\u003c\/strong\u003e Collagen and glucosamine require continuous use for at least 8 to 12 weeks for the cartilage support effects to become clinically noticeable. Daily consistency is more important than the exact timing of consumption.\u003c\/p\u003e","brand":"HSN","offers":[{"title":"Default Title","offer_id":52705355956571,"sku":null,"price":1.8,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1005\/0250\/3771\/files\/HSN-COLLAGENJOINTHEALTHPOWDER.webp?v=1777498902","url":"https:\/\/brothers-club.com\/en\/products\/product_69abafb5-2322-4956-bb00-480f4110dc07","provider":"Brother's Club","version":"1.0","type":"link"}