{"product_id":"product_390d666f-179a-4dfe-b4e4-f41b0631e5c9","title":"HSN - GABA | 500mg \u0026 100caps","description":"\u003ch2 class=\"text-text-100 mt-3 -mb-1 text-[1.125rem] font-bold\"\u003eAbout the Product\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eGABA 500 mg from HSN's EssentialSeries line is a food supplement in vegetable capsules based on 500 mg of gamma-aminobutyric acid (GABA) per capsule, enriched with pantothenic acid (Vitamin B5) and Vitamin B6 as complementary cofactors for neurotransmitter metabolism. GABA is the main inhibitory neurotransmitter in the mammalian central nervous system, present in 30 to 40% of brain neurons, and responsible for the balance between neuronal excitation and inhibition that determines the state of calmness, relaxation, and sleep quality. With 1 capsule per day, preferably taken before bedtime, GABA 500 mg HSN supports natural relaxation, stress management, and sleep quality. Vegan, gluten-free, allergen-free, and GMO-free. Health claim awaiting European authorization from EFSA.\u003c\/p\u003e\n\u003ch2 class=\"text-text-100 mt-3 -mb-1 text-[1.125rem] font-bold\"\u003eBenefits\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eGABA: the main inhibitory neurotransmitter of the central nervous system:\u003c\/strong\u003e GABA (gamma-aminobutyric acid) is synthesized in the brain from glutamate, in a process catalyzed by the enzyme glutamate decarboxylase (which requires Vitamin B6 as a cofactor). It is released by GABAergic neurons and binds to GABA-A and GABA-B receptors in other neurons, producing a hyperpolarization of the neuronal membrane that decreases the probability of action potential firing, resulting in an inhibition of nerve transmission. This inhibitory effect is the mechanism responsible for the feeling of calmness, relaxation, and anxiety reduction that GABA provides. Low levels of GABA or its receptor function are associated with sleep disorders, anxiety, chronic stress, and some forms of epilepsy. Oral supplementation with GABA aims to increase the availability of this neurotransmitter in the nervous system.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eRelaxation, stress and anxiety reduction:\u003c\/strong\u003e GABA supplementation has been associated in clinical studies with a state of increased relaxation and a reduction in the subjective perception of stress and anxiety. A study published in 2006 (Abdou et al.) documented relaxation effects and immune potentiation with oral administration of GABA in humans, with changes in brain wave patterns (increase in alpha waves, associated with an alert relaxed state) detected by electroencephalogram. The 500 mg dose per capsule from HSN corresponds to the reference dose documented as effective in relaxation studies with oral GABA administration.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eSupport for sleep quality and falling asleep:\u003c\/strong\u003e GABA plays a fundamental role in sleep regulation, being the inhibitory neurotransmitter primarily responsible for the transition from wakefulness to sleep and for maintaining deep sleep (NREM). Supplementation with GABA before bedtime aims to facilitate this neurological transition, reducing excessive brain activity that is the main cause of difficulty falling asleep and maintaining sleep. HSN positions GABA 500 mg as part of its sleep support protocol, often combined with Melatonin, Valerian, and Magnesium Bisglycinate for a synergistic effect.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eSupport for GH (growth hormone) secretion during sleep:\u003c\/strong\u003e GABA has a documented relationship with human growth hormone (HGH) secretion, especially in the immediate post-workout period and during deep sleep. HGH is secreted in pulses during slow-wave NREM sleep, which is precisely the phase of sleep most dependent on GABAergic activity. Studies document that GABA supplementation can increase plasma GH levels at rest and immediately after exercise, contributing to muscle development, tissue repair, and fat metabolism, making it especially relevant for athletes who aim to optimize recovery during sleep.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003ePantothenic Acid (B5) for energy metabolism, neurotransmitter synthesis, and fatigue reduction:\u003c\/strong\u003e Pantothenic acid (Vitamin B5), as recognized by EFSA, demonstrably contributes to normal energy metabolism, to the normal synthesis and metabolism of steroid hormones, Vitamin D, and some neurotransmitters, to normal intellectual performance, and to the reduction of tiredness and fatigue. The inclusion of B5 in the HSN GABA 500 mg formula is particularly relevant because acetylcholine synthesis (another neurotransmitter with a role in cognitive function and sleep) requires acetyl-CoA, a metabolite whose metabolism depends on pantothenic acid as a cofactor.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eVitamin B6 for normal nervous system function and GABA metabolism:\u003c\/strong\u003e Vitamin B6 (pyridoxine), as recognized by EFSA, demonstrably contributes to the normal functioning of the nervous system and to normal energy metabolism. More specifically, Vitamin B6 is the essential cofactor of the enzyme glutamate decarboxylase (GAD), which catalyzes the conversion of glutamate to GABA within neurons. Without sufficient B6, endogenous GABA synthesis is compromised, even with adequate glutamate availability. The inclusion of Vitamin B6 in the formula directly complements the activity of supplemented GABA, simultaneously supporting the endogenous synthesis of the neurotransmitter.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eVegan, gluten-free, allergen-free, GMO-free:\u003c\/strong\u003e HSN GABA 500 mg is formulated with a vegetable HPMC (hydroxypropyl methylcellulose) capsule, without animal gelatin, and with a complete absence of declared food allergens, making it suitable for the widest possible spectrum of diets and dietary restrictions.\u003c\/p\u003e\n\u003ch2 class=\"text-text-100 mt-3 -mb-1 text-[1.125rem] font-bold\"\u003eUses\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eBefore bedtime:\u003c\/strong\u003e Take 1 capsule 30 to 60 minutes before bedtime with water. For sleep quality and falling asleep support, this is the most documented and recommended timing.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eAfter training:\u003c\/strong\u003e For athletes who want to take advantage of GABA's effect on GH secretion, take 1 capsule immediately after intense training, ideally in combination with a fast-absorbing protein source to maximize the anabolic signal.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eHSN complete sleep protocol:\u003c\/strong\u003e Combine GABA 500 mg with Magnesium Bisglycinate (2 capsules), Melatonin and\/or Valerian (1 capsule) before bedtime for comprehensive support for relaxation and sleep quality, as recommended by HSN's \"Combat Insomnia\" pack.\u003c\/p\u003e","brand":"HSN","offers":[{"title":"Default Title","offer_id":52705355596123,"sku":null,"price":10.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1005\/0250\/3771\/files\/HSN-GABA_500mg.webp?v=1777499885","url":"https:\/\/brothers-club.com\/en\/products\/product_390d666f-179a-4dfe-b4e4-f41b0631e5c9","provider":"Brother's Club","version":"1.0","type":"link"}