{"product_id":"product_195bf0d2-687b-4c90-9b80-5fb046729bb9","title":"HSN - CHROMIUM PICOLINATE | 200caps \u0026 200mg","description":"\u003ch2 class=\"text-text-100 mt-3 -mb-1 text-[1.125rem] font-bold\"\u003eAbout the Product\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eHSN's EssentialSeries Chromium Picolinate 200 mcg is a food supplement in vegetable capsules based on chromium picolinate, the most bioavailable form of chromium available for oral supplementation. Each capsule provides 200 mcg of elemental Chromium (not from the total salt), which represents 500% of the European Nutrient Reference Value (NRV) for Chromium (40 mcg\/day). Chromium is an essential trace element that the body cannot synthesize endogenously, and it must be obtained exclusively through diet or supplementation. With EFSA-approved health claims for normal macronutrient metabolism and the maintenance of normal blood glucose levels, Chromium is especially relevant as a supplement for individuals with goals of glycemic control, weight management, and carbohydrate metabolism support. Vegan, gluten-free, non-GMO, allergen-free. Available in 30, 120, and 240 capsules.\u003c\/p\u003e\n\u003ch2 class=\"text-text-100 mt-3 -mb-1 text-[1.125rem] font-bold\"\u003eBenefits\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eChromium: essential mineral with EFSA-approved health claims for metabolism and glycemia:\u003c\/strong\u003e Chromium is an essential trace element classified as such by the EFSA (European Food Safety Authority), with two approved and specific health claims: Chromium contributes to the normal metabolism of macronutrients (proteins, carbohydrates, and fats) and Chromium contributes to the maintenance of normal blood glucose levels. These two EFSA-approved claims distinguish Chromium from many other micronutrients for which health claims related to glycemia are still awaiting approval, making it one of the few minerals with a solid European regulatory basis for these specific functions.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eChromium picolinate: the form with the highest documented oral bioavailability:\u003c\/strong\u003e Chromium exists in different forms of supplementation (chromium chloride, chromium nicotinate, yeast chromium, chromium picolinate), which differ significantly in their oral bioavailability. Chromium picolinate is formed by the conjugation of trivalent chromium (Cr3+) with picolinic acid, a natural tryptophan metabolite. Picolinic acid forms stable chelates with chromium that are more water-soluble and more resistant to hydrolysis in the gastrointestinal environment than simple inorganic forms. Comparative bioavailability studies document that chromium picolinate is absorbed much more efficiently than chromium chloride (the most common inorganic form), with absorption estimates 10 to 20 times higher in animal models.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eTransparency in declaration: 200 mcg of elemental Chromium, not from the salt:\u003c\/strong\u003e HSN highlights an important transparency aspect in the labeling of its Chromium Picolinate: the declared 200 mcg refers to pure elemental Chromium, not the total weight of the chromium picolinate salt. Many manufacturers on the market declare the total weight of the chromium picolinate salt (which includes picolinic acid as part of the molecule, without specific Chromium activity), which results in a real amount of elemental Chromium much lower than declared. For example, a product declaring \"200 mcg of chromium picolinate\" typically contains only ~32 mcg of elemental Chromium (since Chromium represents only ~16% of the molecular weight of chromium picolinate), much less than the declared 200 mcg. HSN transparently declares that each capsule contains 200 mcg of elemental Chromium (the biologically active part), ensuring that the user receives and can validly compare it with other products.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eRole of Chromium in insulin signaling and glucose metabolism:\u003c\/strong\u003e The molecular mechanism by which Chromium supports normal glucose metabolism primarily involves its participation as a cofactor of chromium-binding oligopeptide (chromodulin or LMW-Cr), an endogenous molecule that potentiates intracellular signaling of the insulin receptor. When insulin binds to its receptor on the cell surface, it promotes the translocation of the GLUT4 glucose transporter to the plasma membrane and activates an intracellular phosphorylation cascade. Chromium (via chromodulin) amplifies these intracellular signaling cascades, increasing the efficiency of insulin-mediated glucose uptake. This function of potentiating insulin signaling is the mechanism by which Chromium contributes to the maintenance of normal blood glucose levels.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eSupport for macronutrient metabolism for athletes and people on caloric restriction:\u003c\/strong\u003e In addition to its role in glucose metabolism, Chromium has documented influence on protein and fat metabolism. Studies document that chromium picolinate supplementation can modestly increase fat oxidation and reduce protein catabolism in contexts of physical exercise and caloric restriction, which is the basis for its historical use as a body composition supplement in sports. Although the effects on body composition are modest compared to other supplements (such as creatine or protein), Chromium is often included in weight loss and glycemic control formulas as a broad-spectrum metabolic support component.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003e200 mcg dose: 500% of the European NRV, basis for most clinical studies:\u003c\/strong\u003e The dose of 200 mcg of elemental Chromium per capsule represents 500% of the European Nutrient Reference Value (40 mcg\/day), established as the dose for healthy adults that prevents deficiency. The supplementation dose typically used in reference clinical studies ranges from 200 to 1000 mcg\/day of elemental Chromium, with most studies using 200 to 400 mcg\/day. The 200 mcg per capsule dose allows the user to easily adjust the dose between 200 and 600 mcg\/day (1 to 3 capsules\/day) according to their specific needs, remaining within the documented safe doses (up to 1000 mcg\/day of chromium picolinate are considered safe by most regulatory authorities for use in supplementation).\u003c\/p\u003e\n\u003ch2 class=\"text-text-100 mt-3 -mb-1 text-[1.125rem] font-bold\"\u003eUses\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eRecommended dose:\u003c\/strong\u003e Take 1 capsule daily before physical activity or with the main meal. For specific support for post-prandial glycemic control, you can take 1 capsule with each of the 3 main meals (up to 3 capsules\/day = 600 mcg of elemental Chromium\/day), within the documented safe doses.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eTiming:\u003c\/strong\u003e Taking it with carbohydrate-containing meals maximizes the functional relevance of Chromium for supporting glucose metabolism, as Chromium potentiates the insulin response that occurs after carbohydrate intake.\u003c\/p\u003e","brand":"HSN","offers":[{"title":"Default Title","offer_id":52705356906843,"sku":null,"price":11.9,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1005\/0250\/3771\/files\/HSN-PICOLINATODECROMIO_200mg.webp?v=1777501893","url":"https:\/\/brothers-club.com\/en\/products\/product_195bf0d2-687b-4c90-9b80-5fb046729bb9","provider":"Brother's Club","version":"1.0","type":"link"}