About the Product
Life Pro Nutrition B Complex is a dietary supplement in VCAPS vegetable capsules with a complex of 8 B vitamins (B1, B2, B3, B5, B6, B7, B9, and B12) enriched with Inositol and Choline Bitartrate, in a formula designed for athletes and people with high caloric expenditure due to intense physical activity. B vitamins are water-soluble and essential enzymatic cofactors in energy metabolism (they convert dietary carbohydrates, proteins, and fats into ATP) and neurological function. As they are water-soluble and not stored by the body in significant amounts, they require regular intake through diet or supplementation, and their needs increase proportionally to training volume and caloric expenditure. 1 capsule/day after a meal. 60 capsules (60 days). Vegan.
Benefits
The 8 B vitamins: indispensable cofactors of energy metabolism and neurological function:
B vitamins are a set of 8 chemically distinct but metabolically interconnected water-soluble vitamins that function as cofactors (in the form of coenzymes) for hundreds of enzymatic reactions in energy metabolism and macromolecule synthesis. All have approved EFSA health claims and are mandatory on food supplement labels in the EU. EFSA has approved specific claims for each B vitamin, the most relevant for athletes being: contribution to normal energy metabolism (B1, B2, B3, B5, B6, B7, B12), reduction of tiredness and fatigue (B2, B3, B5, B6, B9, B12), normal functioning of the nervous system (B1, B2, B3, B6, B7, B12), normal functioning of the immune system (B6, B9, B12), and normal amino acid synthesis (B6).
Vitamin B1 (thiamine/thiamine hydrochloride): the cofactor of carbohydrate metabolism and cardiac function:
Thiamine (B1), in its active form of thiamine pyrophosphate (TPP), is the essential cofactor of three key enzymes in carbohydrate metabolism: pyruvate dehydrogenase (conversion of pyruvate to acetyl-CoA, linking glycolysis to the Krebs cycle), alpha-ketoglutarate dehydrogenase (a step in the Krebs cycle that produces succinyl-CoA and NADH), and transketolase (pentose phosphate pathway). Thiamine deficiency directly compromises ATP production from carbohydrates, with a priority impact on brain and heart tissue (which rely almost exclusively on glucose as fuel). For athletes with high carbohydrate intake and a high glycolysis rate, thiamine is one of the most functionally relevant B vitamins.
Vitamin B2 (riboflavin): the cofactor of the respiratory chain and fat metabolism:
Riboflavin (B2) is a precursor of the coenzymes FAD (flavin adenine dinucleotide) and FMN (flavin mononucleotide), which are essential electron transporters in the mitochondrial respiratory chain (complexes I and II) and in multiple oxidation-reduction reactions of fatty acid metabolism (acyl-CoA dehydrogenase), amino acids, and xenobiotics. EFSA has approved claims for contribution to normal energy metabolism, maintenance of normal red blood cells, maintenance of normal skin, mucous membranes, and vision, and protection of cells from oxidative stress.
Vitamin B3 (niacin/nicotinamide): the precursor of NAD+ and the regulator of cellular metabolism:
Niacin (B3/nicotinamide) is a precursor of NAD+ (nicotinamide adenine dinucleotide), the most abundant electron transfer coenzyme in human cells and a cofactor of over 400 enzymatic reactions (much more than any other coenzyme), including ATP production steps in glycolysis, beta-oxidation of fatty acids, and the Krebs cycle. NAD+ is also a substrate of sirtuins (NAD+-dependent deacetylases with functions in gene silencing, DNA repair, and mitochondrial metabolism regulation) and PARP-1 (poly-ADP-ribose polymerase, a DNA repair enzyme). EFSA has approved claims for contribution to normal energy metabolism and the reduction of tiredness and fatigue.
Vitamin B5 (pantothenic acid/calcium D-pantothenate): the precursor of coenzyme A:
Pantothenic acid (B5) is the precursor for the synthesis of Coenzyme A (CoA), the central molecule of energy metabolism that activates fatty acids for beta-oxidation (in the form of acyl-CoA), transports acetyl groups in the Krebs cycle (in the form of acetyl-CoA), and participates in the synthesis of cholesterol, steroid hormones, and phospholipids. Without B5, the body cannot synthesize adequate amounts of CoA, compromising the ability to oxidize fatty acids and complete the Krebs cycle. EFSA has approved the claim of contribution to the normal synthesis and metabolism of steroid hormones, vitamin D, and some neurotransmitters, and to the reduction of tiredness and fatigue.
Vitamin B6 (pyridoxine/pyridoxine hydrochloride): the cofactor of amino acid and neurotransmitter metabolism:
Pyridoxine (B6), in its active form of pyridoxal-5-phosphate (PLP), is the cofactor of over 100 enzymatic reactions in amino acid metabolism (transaminations, decarboxylations, racemizations), including the synthesis of neurotransmitters (serotonin via tryptophan hydroxylase, dopamine via DOPA decarboxylase, GABA via glutamate decarboxylase, histamine via histidine decarboxylase) and endogenous carnitine synthesis (carnitine biosynthesis requires B6 as a cofactor). It also has approved EFSA claims for normal homocysteine metabolism (together with B9 and B12) and for the regulation of hormonal activity.
Vitamin B7 (biotin): the cofactor of carboxylases and macronutrient metabolism:
Biotin (B7) is the cofactor of carboxylases (enzymes that incorporate carbon dioxide into organic molecules), including acetyl-CoA carboxylase (fatty acid synthesis), pyruvate carboxylase (gluconeogenesis), propionyl-CoA carboxylase (branched-chain amino acid metabolism), and 3-methylcrotonoyl-CoA carboxylase (leucine metabolism). EFSA has approved claims for contribution to normal energy metabolism, normal functioning of the nervous system, maintenance of normal hair and skin, and maintenance of normal mucous membranes.
Vitamin B9 (folic acid): the cofactor of DNA and red blood cell synthesis:
Folic acid (B9, pteroylmonoglutamic acid) is the precursor of tetrahydrofolate (THF), the coenzyme that transfers one-carbon groups in DNA synthesis reactions (purine and thymidylate synthesis) and in homocysteine metabolism (with B12 and B6). B9 deficiency compromises DNA synthesis and cell division, with a priority impact on highly proliferating tissues (bone marrow, intestinal mucosa), causing megaloblastic anemia and neural tube defects during embryogenesis. EFSA has approved claims for normal amino acid synthesis, normal immune function, normal hematopoiesis, and reduction of tiredness.
Vitamin B12 (cyanocobalamin): the essential vitamin for red blood cells and myelin:
Cyanocobalamin (B12) is a cofactor for two human enzymes: methionine synthase (which converts homocysteine to methionine, together with folic acid, being essential for DNA methylation and SAM synthesis) and methylmalonyl-CoA mutase (metabolism of branched-chain amino acids and odd-chain fatty acids). B12 is essential for myelin synthesis (the sheath of nerve axons) and for normal hematopoiesis (deficiency causes megaloblastic anemia identical to that of B9 deficiency). B12 is only naturally present in animal-derived foods, making its supplementation particularly relevant for vegetarians and vegans.
Inositol and Choline Bitartrate: the two "pseudovitamins" of the B group with lipotropic and cell signaling functions:
Inositol (myo-inositol, sometimes called vitamin B8) and choline (sometimes called vitamin B4 or J) are compounds with coenzyme/cofactor functions that were historically classified as B vitamins but do not have this formal status. Both have been described in detail in the Lipopro and Ovapro sections of Life Pro. In the context of B Complex, their inclusion adds lipotropic support (hepatic fat metabolism via phosphatidylcholine and phosphatidylinositol) and cell signaling (IP3 via inositol, acetylcholine via choline) to the base of the 8 B vitamins.
Usage
Recommended dosage: Take 1 capsule/day after the main meal, with plenty of water. Taking it with food improves the absorption of water-soluble vitamins and reduces the risk of gastrointestinal discomfort. B vitamins are water-soluble, and the excess is excreted in the urine, making toxicity very unlikely at standard supplementation doses. 60 capsules = 60 days with 1 capsule/day.
