Life Pro - EAAs Evidenced Formula | 300g

About the Product

Life Pro Nutrition's Evidenced Formula EAAs are a powdered amino acid supplement based on the full profile of the 9 essential amino acids (EAAs: histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine) in optimized proportions for muscle protein synthesis, enriched with 2 additional conditionally essential amino acids (L-cysteine and L-tyrosine) due to scientific evidence of their effectiveness. The 11-amino-acid formula distinguishes itself from simple BCAA supplements (which provide only leucine, isoleucine, and valine) by providing the full spectrum of amino acids that the body cannot synthesize endogenously and that are necessary for the synthesis of new muscle proteins. Dose: 14 g (or 0.15 to 0.20 g/kg of body weight) in 250 ml of liquid. Immediate absorption without prior digestion. 300 g per pack (~21 servings). Flavors: Lemon, Fruit Blast (blackcurrant), Tropical. Vegan.

Benefits

EAAs vs. BCAAs: why the complete essential amino acid profile is superior for muscle protein synthesis:

For over two decades, BCAAs (leucine, isoleucine, and valine) were the amino acid supplement of choice for strength athletes, based on the premise that leucine is the primary activator of protein synthesis via mTOR and that BCAAs are preferentially oxidized in muscle. However, scientific evidence accumulated over the last decade has revealed a critical limitation of isolated BCAA supplements: for the synthesis of new muscle proteins to occur, the body needs all essential amino acids to be available simultaneously. If only leucine, isoleucine, and valine are available in excess (as with a BCAA supplement), protein synthesis is limited by the availability of the other 6 essential amino acids. The study by Wolfe et al. (2017), published in the Journal of the International Society of Sports Nutrition, conclusively documented that isolated BCAA intake stimulates muscle protein synthesis significantly less than the intake of a complete EAA profile at the same leucine dose, precisely because the other essential amino acids are limiting when only BCAAs are supplied. Additional studies document that complete EAA intake after resistance exercise increases muscle protein synthesis by 50 to 70% compared to isolated BCAAs in controlled crossover trials. This evidence has led to a reorientation of the amino acid supplement market towards complete EAAs, which is precisely the positioning of this formula.

The proportion of each EAA in the formula: the hierarchy of importance for muscle protein synthesis:

The order of ingredients by decreasing quantity (L-Leucine > L-Lysine > L-Isoleucine > L-Valine > L-Threonine > L-Histidine > L-Phenylalanine > L-Methionine > L-Tryptophan) reflects the hierarchy of importance of each amino acid for muscle protein synthesis, modeled based on human skeletal muscle aminoacidogram studies and clinical efficacy data. L-Leucine is the most represented amino acid in the formula, as it is the primary activator of the mTORC1 complex (the central regulator of protein synthesis), with a documented dose-response where higher doses of leucine (typically 2 to 3 g per dose) maximize the anabolic stimulus. L-Lysine is the second most represented amino acid, as it is often the limiting amino acid in cereal-based diets and is essential for the synthesis of carnitine, collagen, and antibodies. L-Tryptophan is the amino acid in the smallest amount, as it is the rarest in muscle tissues and required in the smallest proportion for protein synthesis. This hierarchy ensures that no amino acid becomes limiting for protein synthesis when the dose is adequate.

L-Cysteine and L-Tyrosine: the two conditionally essential amino acids that elevate the formula beyond standard EAAs:

Conditionally essential amino acids are amino acids that the body can synthesize endogenously under normal conditions, but whose endogenous synthesis rate can become insufficient in situations of high metabolic stress (high-intensity training, inflammation, illness, caloric restriction). Life Pro has added two conditionally essential amino acids to the EAA formula based on scientific evidence. L-Cysteine is the limiting amino acid for the endogenous synthesis of glutathione (the main intracellular antioxidant), and its availability is critical during intense exercise (which increases the production of free radicals and glutathione consumption). In addition to antioxidant support via glutathione, cysteine is a sulfur-containing amino acid essential for the synthesis of proteins with disulfide bonds (such as immunoglobulins and keratins of skin and hair). L-Tyrosine is the precursor of catecholaminergic neurotransmitters (dopamine, norepinephrine, adrenaline) and thyroid hormones (T3 and T4). During intense physical exercise, tyrosine metabolism is accelerated by increased catecholamine production, and its availability becomes limiting for maintaining cognitive function, mood, and motivation in contexts of intense physical and mental fatigue. Clinical studies document that tyrosine supplementation in situations of acute stress (intense exercise, sleep deprivation, cold exposure) improves cognitive performance and stress tolerance compared to placebo.

Immediate absorption without the need for digestion: plasma availability in minutes:

Free amino acids (in the form of powdered L-amino acids, as present in this formula) do not require prior proteolytic digestion to be absorbed in the small intestine, unlike intact proteins (whey, casein, pea protein) which need to be hydrolyzed by gastric and pancreatic proteases into peptides and amino acids before absorption. Free L-amino acids are directly transported into the bloodstream by specific intestinal mucosal transporters (such as the SLC7A5 transporter for neutral amino acids, SLC6A19 for zwitterionic neutral amino acids, and SLC3A1/SLC7A9 for cationic amino acids like lysine and arginine), raising plasma amino acid levels within 15 to 30 minutes after ingestion. This absorption speed is 2 to 3 times faster than whey protein (the fastest known digesting protein) and is especially advantageous in the intra-workout context (consumption during exercise) where the goal is to maintain plasma amino acid levels available to the muscle during prolonged efforts without the gastrointestinal discomfort that intact protein digestion during exercise can cause.

Vegan and bacterially synthesized: high-purity amino acids of non-animal origin:

Unlike many amino acid supplements on the market where some amino acids (namely L-leucine, L-isoleucine, L-valine, and L-lysine) are often produced by hydrolysis of animal proteins (chicken feather keratin, human hair, soy proteins), Life Pro's EAAs are produced by bacterial fermentation or chemical synthesis from plant substrates, ensuring verifiable vegan origin. This characteristic is confirmed by Life Pro in response to a customer who specifically inquired about the origin of the amino acids.

Uses

Recommended dose: Dissolve 14 g (or 0.15 to 0.20 g per kg of body weight) in 250 ml of water, juice, or another beverage of choice. Shake well. EAAs can be consumed at any time of day: on an empty stomach (to stimulate morning protein synthesis without complete protein calories), with low-protein meals (to supplement the essential amino acid intake of an incomplete meal), or before, during, or after training (to stimulate peri-workout protein synthesis and protect muscle from exercise-induced catabolism).